The research of atropisomerism in synthetic chemistry has drawn growing attention in recent years, owing to its prevalence and importance to natural products, material science and pharmaceutical chemistry. N-Heterocyclic carbene (NHC)-catalyzed reactions for atropisomer construction has emerged as a burgeoning and promising research topic in recent years. This review mainly summarizes the examples for access to atropisomers catalyzed by NHC catalysis, along with the introduction for NHC precursors and patterns of atropisomers involved. To help understanding the progress of NHC-catalyzed atropisomer construction, this review has been documented according to the following four different strategies: annulation, kinetic resolutions, asymmetric desymmetrizations and central-to-axial chirality conversions. Novel methods for NHC-catalyzed atroposelective synthesis are therefore encouraged, including application of novel NHC intermediates and catalytic modes, in the very near future.

近年来，合成化学中的阻转异构研究因其在天然产物、材料科学和药物化学中的普遍性和重要性而受到越来越多的关注。近年来，N-杂环卡宾（NHC）催化的阻转异构体构建反应已成为一个新兴且有前途的研究课题。本综述主要总结了获得NHC催化催化的阻转异构体的例子，以及NHC前体的介绍和所涉及的阻转异构体的模式。为了帮助理解 NHC 催化的阻转异构体构建的进展，本综述根据以下四种不同的策略进行了记录：环化、动力学分辨率、不对称去对称化和中心轴手性转换。