Extracellular vesicles from pancreatic ductal adenocarcinoma endoscopic ultrasound-fine needle aspiration samples contain a protein barcode,Journal of Hepato-Biliary-Pancreatic Sciences

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Extracellular vesicles from pancreatic ductal adenocarcinoma endoscopic ultrasound-fine needle aspiration samples contain a protein barcode
Journal of Hepato-Biliary-Pancreatic Sciences ( IF 3 ) Pub Date : 2021-09-23 , DOI: 10.1002/jhbp.1048
Hiroyuki Inoue ₁ , Akiko Eguchi _{1,

2} , Yoshinao Kobayashi _{1,

3} , Eri Usugi ₄ , Reiko Yamada ₁ , Junya Tsuboi ₁ , Teruo Akuta ₅ , Noriyuki Horiki ₁ , Motoh Iwasa ₁ , Yoshiyuki Takei ₁

Affiliation

The survival rate of pancreatic ductal adenocarcinoma (PDAC) is very poor because early detection is difficult. Extracellular vesicles (EVs) are released from cells associating with the cellular condition and circulated in the blood. We aimed to identify EV proteins from endoscopic ultrasound-fine needle aspiration (EUS-FNA) biopsy samples in order to develop novel biomarkers for PDAC.

中文翻译：

胰腺导管腺癌内镜超声细针抽吸样本的细胞外囊泡含有蛋白质条形码

胰腺导管腺癌 (PDAC) 的存活率非常低，因为早期发现很困难。细胞外囊泡 (EV) 从与细胞状况相关的细胞中释放出来并在血液中循环。我们旨在从内窥镜超声细针穿刺 (EUS-FNA) 活检样本中鉴定 EV 蛋白，以开发新的 PDAC 生物标志物。

更新日期：2021-09-23

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