A real-world study of alemtuzumab in a cohort of Italian patients,European Journal of Neurology

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A real-world study of alemtuzumab in a cohort of Italian patients
European Journal of Neurology ( IF 4.5 ) Pub Date : 2021-09-24 , DOI: 10.1111/ene.15121
Cinzia Valeria Russo ₁ , Francesco Saccà ₁ , Jessica Frau ₂ , Pietro Annovazzi ₃ , Elisabetta Signoriello ₄ , Simona Bonavita ₄ , Roberta Grasso ₅ , Marinella Clerico ₆ , Cinzia Cordioli ₇ , Alice Laroni ₈ , Marco Capobianco ₉ , Valentina Torri Clerici ₁₀ , Arianna Sartori ₁₁ , Paola Cavalla ₁₂ , Giorgia Teresa Maniscalco ₁₃ , Sara La Gioia ₁₄ , Francesca Caleri ₁₅ , Alessia Giugno ₁₆ , Rosa Iodice ₁ , Antonio Carotenuto ₁ , Eleonora Cocco ₂ , Giuseppe Fenu ₂ , Mauro Zaffaroni ₃ , Damiano Baroncini ₃ , Giacomo Lus ₄ , Antonio Gallo ₁₇ , Stefania Federica De Mercanti ₆ , Caterina Lapucci ₈ , Valeria Di Francescantonio ₅ , Laura Brambilla ₁₀ , Maria Pia Sormani ₁₈ , Alessio Signori ₁₈

Affiliation

NSRO Department, University of Naples Federico II, Napoli, Italy.
Centro Sclerosi Multipla, ASSL Cagliari (ATS Sardegna); Dipartimento di Scienze Mediche e Sanità Pubblica, University of Cagliari, Cagliari, Italy.
Multiple Sclerosis Center, ASST della Valle Olona, Hospital of Gallarate, Gallarate, Italy.
University of Campania Luigi Vanvitelli, Napoli, Italy.
University of Foggia, Foggia, Italy.
Dipartimento di Scienze Cliniche e Biologiche, University of Torino, Torino, Italy.
Multiple Sclerosis Center, ASST Spedali Civili di Brescia, Montichiari Hospital, Montichiari, Italy.
Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health and Center of Excellence for Biomedical Research (CEBR) and IRCCS San Martino-IST, University of Genova, Genova, Italy.
SC Neurologia e Centro di Riferimento Regionale SM - AOU S. Luigi, Orbassano, Torino, Italy.
Neuro-Immunology and Neuromuscolar Diseases Unit, IRCCS Foundation Carlo Besta Neurological Institute, Milano, Italy.
Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, ASUGI, University of Trieste, Trieste, Italy.
MS Center, City of Health & Science University Hospital, Torino, Italy.
Multiple Sclerosis Center "A. Cardarelli" Hospital, Naples, Italy.
Centro Sclerosi Multipla, ASST Papa Giovanni XXIII, Bergamo, Italy.
Neurology Department, F. Tappeiner Hospital Meran (BZ) of Neurology, Franz Tappeiner Hospital, Merano, Italy.
Institute of Neurology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
University of Campania "Luigi Vanvitelli", Napoli, Italy.
Department of Health Sciences (DISSAL), Section of Biostatistics, University of Genova, Genova, Italy.

Real-world data on alemtuzumab are limited and do not provide evidence of its effectiveness after various disease-modifying therapies (DMTs). Our aim was to provide real-world data on the impact of clinical variables and previous DMTs on clinical response to alemtuzumab.

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