Resolving the spatial distribution of the transcriptome at a subcellular level can increase our understanding of biology and diseases. To facilitate studies of biological functions and molecular mechanisms in the transcriptome, we updated RNALocate, a resource for RNA subcellular localization analysis that is freely accessible at http://www.rnalocate.org/ or http://www.rna-society.org/rnalocate/. Compared to RNALocate v1.0, the new features in version 2.0 include (i) expansion of the data sources and the coverage of species; (ii) incorporation and integration of RNA-seq datasets containing information about subcellular localization; (iii) addition and reorganization of RNA information (RNA subcellular localization conditions and descriptive figures for method, RNA homology information, RNA interaction and ncRNA disease information) and (iv) three additional prediction tools: DM3Loc, iLoc-lncRNA and iLoc-mRNA. Overall, RNALocate v2.0 provides a comprehensive RNA subcellular localization resource for researchers to deconvolute the highly complex architecture of the cell.

中文翻译：

---

RNALocate v2.0：更新的 RNA 亚细胞定位资源，增加了覆盖率和注释

在亚细胞水平上解决转录组的空间分布可以增加我们对生物学和疾病的理解。为了促进转录组中生物学功能和分子机制的研究，我们更新了 RNALocate，这是一种用于 RNA 亚细胞定位分析的资源，可在 http://www.rnalocate.org/ 或 http://www.rna-society 上免费访问。 org/rnalocate/. 与 RNALocate v1.0 相比，2.0 版本的新功能包括：（i）数据源的扩展和物种的覆盖；(ii) 包含亚细胞定位信息的 RNA-seq 数据集的整合和整合；(iii) RNA 信息的添加和重组（RNA 亚细胞定位条件和方法描述图、RNA 同源性信息、RNA 相互作用和 ncRNA 疾病信息）和（iv）三个额外的预测工具：DM3Loc、iLoc-lncRNA 和 iLoc-mRNA。总体而言，RNALocate v2.0 为研究人员提供了全面的 RNA 亚细胞定位资源，以解卷积高度复杂的细胞结构。