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Swept-source OCT reduces the risk of axial length measurement errors in eyes with cataract and epiretinal membranes.
PLOS ONE ( IF 2.9 ) Pub Date : 2021-09-22 , DOI: 10.1371/journal.pone.0257654
Francesco Faraldi 1 , Carlo Alessandro Lavia 1 , Marco Nassisi 2, 3 , Raphael A Kilian 4 , Daniela Bacherini 5 , Stanislao Rizzo 6, 7, 8
Affiliation  

AIMS To compare the biometric data from partial coherence interferometry (PCI) and swept-source OCT (SS-OCT) in patients with age-related cataract and epiretinal membrane (ERM): ERM, ERM with foveoschisis and macular pseudohole. METHODS 49 eyes of 49 subjects including 36 ERM, 9 ERM foveoschisis and 4 macular pseudohole were analysed to evaluate the axial length (AL) measurements and the presence of AL measurement errors, defined basing on the shape of the biometric output graphs and on the concordance of AL values between instruments. Eyes with ERM were divided in four stages according to OCT features (i.e. presence/absence of the foveal pit, presence of ectopic inner foveal layers, disrupted retinal layers). RESULTS The devices provided similar mean AL measurements in all subgroups, with differences <0.1 mm in 41/49 cases (83.6%). AL measurement errors were observed in ERM stages 3 and 4, characterized by ectopic inner foveal layers, and were significantly more frequent with the PCI (8/17, 47%) as compared with the SS-OCT device (2/17, 12%), p = 0.02. The refractive prediction error in cases with AL measurement errors was significantly greater using the PCI compared to the SS-OCT device (p<0.05). CONCLUSION Both devices provide reliable biometric data in the majority of patients and can be used in the preoperative assessment of patients with age-related cataract and ERM. In eyes with ectopic inner foveal layers, attention should be paid as AL measurement and refractive prediction errors may occur, more frequently with the PCI device.

中文翻译:


扫频 OCT 可降低患有白内障和视网膜前膜的眼睛发生眼轴长度测量错误的风险。



目的 比较年龄相关性白内障和视网膜前膜 (ERM) 患者的部分相干干涉测量 (PCI) 和扫源 OCT (SS-OCT) 的生物特征数据:ERM、伴有中央凹劈裂和黄斑假孔的 ERM。方法 对 49 名受试者的 49 只眼睛(包括 36 个 ERM、9 个 ERM 中央凹劈裂和 4 个黄斑假孔)进行分析,以评估眼轴长度 (AL) 测量值以及 AL 测量误差的存在,这些误差根据生物特征输出图的形状和一致性进行定义仪器之间的 AL 值。根据 OCT 特征(即存在/不存在中心凹凹、存在异位内中心凹层、破坏的视网膜层),将 ERM 眼睛分为四个阶段。结果 设备在所有亚组中提供相似的平均 AL 测量值,其中 41/49 例 (83.6%) 的差异为 <0.1 mm。在 ERM 3 期和 4 期中观察到 AL 测量误差,其特征是异位内中心凹层,与 SS-OCT 设备(2/17,12%)相比,PCI 中的 AL 测量误差(8/17,47%)明显更常见。 ),p = 0.02。与 SS-OCT 设备相比,使用 PCI 时存在 AL 测量误差的屈光预测误差明显更大 (p<0.05)。结论 这两种设备都能为大多数患者提供可靠的生物识别数据,可用于年龄相关性白内障和 ERM 患者的术前评估。对于异位内中心凹层的眼睛,应注意 AL 测量和屈光预测误差,尤其是使用 PCI 设备时可能会出现误差。
更新日期:2021-09-22
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