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The liquid micro junction-surface sampling probe (LMJ-SSP); a versatile ambient mass spectrometry interface
Analyst ( IF 3.6 ) Pub Date : 2021-09-08 , DOI: 10.1039/d1an00725d
David Simon 1 , Richard Oleschuk 1
Affiliation  

Ambient ionization methods have become important tools in mass spectrometry. The LMJ-SSP can significantly simplify/reduce lengthy sample preparation requirements associated with mass spectrometry analysis. Samples may be introduced through direct contact, insertion and droplet injection, enabling applications from drug discovery and surface analysis to tissue profiling and metabolic mapping. This review examines the underlying principles associated with the LMJ-SSP interface and highlights modifications of the original design that have extended its capability. We summarize different application areas that have exploited the method and describe potential future directions for the adaptable ambient ionization source.

中文翻译:

液体微结面取样探头(LMJ-SSP);多功能环境质谱接口

环境电离方法已成为质谱分析中的重要工具。LMJ-SSP 可以显着简化/减少与质谱分析相关的冗长的样品制备要求。样品可以通过直接接触、插入和液滴注射引入,从而实现从药物发现和表面分析到组织分析和代谢图谱的应用。该评论检查了与 LMJ-SSP 接口相关的基本原理,并重点介绍了扩展其功能的原始设计修改。我们总结了利用该方法的不同应用领域,并描述了适应性环境电离源的潜在未来方向。
更新日期:2021-09-23
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