Selective chemical separation of U without any compromise of analyte concentration even at trace level; is a prerequisite to avoid the spectral interference in Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). “Green” approach based on application of ionic liquid; has been followed to bring down the U concentration below the tolerance limit, prior to the analyses of common metallic constituents (Al, Ca, Cu, Cr, Fe, Mn, Mg, Na, Ni, Pb, and Zn) and critical elements (B, Cd, Ag, Eu, Sm, Gd, and Dy). 'Anion exchange' mechanism was found to be predominantly operative for TBP/C₃PyNTf₂ based separation system during extraction of U, involving 1:2 anionic metal–ligand complex; while, in TBP/n-dodecane, conventional 'solvation' mechanism was operative involving 1:2 neutral metal–ligand complex. The methodologies were optimized (identification of interference free analytical lines, establishing calibration curves, estimation of detection limits, linear dynamic range, precision) using synthetic samples. Statistical t-test was performed to understand reliability of the data. Significant reductions in organic waste volume and sample processing time have been demonstrated by application of ionic liquids. For analysis of common analytes, three contacts of 1.1 M TBP/C₃PyNTf₂/6M HNO₃ were found to be efficient in bringing down the U below tolerance level without much compromise on the concentrations of analytes at trace level. The associated error was within the limits of allowed statistical fluctuation. However, for critical elements, the methodology was not reliable. For them, the sample feed solution should be adjusted to 3 M HNO₃ prior the U removal.

对 U 进行选择性化学分离，即使在痕量水平下也不会对分析物浓度造成任何影响；是避免电感耦合等离子体发射光谱 (ICP-OES) 中光谱干扰的先决条件。基于离子液体应用的“绿色”途径；在分析常见金属成分（Al、Ca、Cu、Cr、Fe、Mn、Mg、Na、Ni、Pb 和 Zn）和关键元素（ B、Cd、Ag、Eu、Sm、Gd 和 Dy）。发现“阴离子交换”机制主要对 TBP/C ₃ PyNTf ₂起作用萃取 U 过程中的基于分离系统，涉及 1:2 阴离子金属-配体配合物；而在 TBP/n-十二烷中，传统的“溶剂化”机制在 1:2 中性金属-配体络合物中起作用。使用合成样品优化方法（识别无干扰分析线、建立校准曲线、估计检测限、线性动态范围、精度）。进行统计t检验以了解数据的可靠性。离子液体的应用已经证明了有机废物量和样品处理时间的显着减少。对于常见分析物的分析，1.1 M TBP/C ₃ PyNTf ₂ /6M HNO _{3 的}三个触点发现可以有效地将 U 降低到容许水平以下，而不会对痕量水平的分析物浓度造成太大影响。相关误差在允许的统计波动范围内。然而，对于关键要素，该方法并不可靠。对于他们来说，在去除 U 之前，应将样品进料溶液调整为 3 M HNO ₃。