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CRISPR/Cas-mediated genome editing in sorghum — recent progress, challenges and prospects
In Vitro Cellular & Developmental Biology - Plant ( IF 2.2 ) Pub Date : 2021-09-22 , DOI: 10.1007/s11627-021-10215-y
Aalap Parikh 1, 2 , Eleanor J. Brant 1, 2 , Mehmet Cengiz Baloglu 1 , Fredy Altpeter 1, 2
Affiliation  

Sorghum is a versatile crop with great potential as a sustainable food, feed, and bioenergy source. To mitigate the severely negative impact of climate change and population growth on food and energy security, further elevation of the crops stress tolerance is urgently needed. Genome editing technologies such as CRISPR/Cas have great potential to accelerate functional genomics and crop improvement by supporting targeted modification of almost any crop gene sequence. We describe the recent progress in genome editing of sorghum. In addition, we review remaining challenges and prospects of emerging gene editing technologies for rapid precision breeding of this crop.



中文翻译:

CRISPR/Cas 介导的高粱基因组编辑——最新进展、挑战和前景

高粱是一种用途广泛的作物,具有作为可持续食品、饲料和生物能源的巨大潜力。为了减轻气候变化和人口增长对粮食和能源安全的严重负面影响,迫切需要进一步提高作物的抗逆性。CRISPR/Cas 等基因组编辑技术通过支持几乎所有作物基因序列的靶向修饰,在加速功能基因组学和作物改良方面具有巨大潜力。我们描述了高粱基因组编辑的最新进展。此外,我们回顾了新兴基因编辑技术在该作物的快速精准育种方面存在的挑战和前景。

更新日期:2021-09-23
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