Iris retraction syndrome (IRS) is an uncommon condition caused by retinal detachment that is characterized by back bowing of the peripheral iris, leading to a deep anterior chamber. It is commonly associated with ocular hypotony, ciliochoroidal detachment, and anterior proliferative vitreoretinopathy. We describe a case of a 66-year-old man presenting with 2 weeks of right eye pain, redness, and iris heterochromia. The patient was diagnosed with IRS secondary to a chronic retinal detachment. Initial management with topical steroids and mydriasis allowed resolution of the iris retraction and heterochromia, normalization of intraocular pressure, and improvement of choroidal detachment. Subsequent vitrectomy with endolaser and oil tamponade led to successful detachment repair. Initial pharmacologic management allows a more controlled approach to the repair of retinal detachment associated with IRS. The patient’s presentation is consistent with the hydrodynamic hypothesis of IRS.
Case Rep Ophthalmol 2021;12:809–815

中文翻译：

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虹膜收缩综合征伴异色症和视网膜脱离的治疗

虹膜回缩综合征 (IRS) 是一种由视网膜脱离引起的罕见疾病，其特征是周边虹膜向后弯曲，导致前房较深。它通常与眼压低、纤毛脉络膜脱离和前增生性玻璃体视网膜病变有关。我们描述了一例 66 岁男性，右眼疼痛、发红和虹膜异色症 2 周。该患者被诊断为继发于慢性视网膜脱离的 IRS。用局部类固醇和瞳孔散大的初始治疗可以解决虹膜回缩和异色症，眼压正常化和脉络膜脱离的改善。随后的玻璃体切除术与内窥镜和油填塞导致了成功的脱离修复。初始药物管理允许更可控的方法来修复与 IRS 相关的视网膜脱离。患者的表现与 IRS 的流体动力学假设一致。
Case Rep Ophthalmol 2021；12:809–815