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Designing a Red-Emitting Viscosity-Sensitive BODIPY Fluorophore for Intracellular Viscosity Imaging
Chemistry - A European Journal ( IF 4.3 ) Pub Date : 2021-09-22 , DOI: 10.1002/chem.202102743
Karolina Maleckaitė 1 , Jelena Dodonova 2 , Stepas Toliautas 3 , Rugilė Žilėnaitė 1 , Džiugas Jurgutis 4 , Vitalijus Karabanovas 4, 5 , Sigitas Tumkevičius 2 , Aurimas Vyšniauskas 1
Affiliation  

Going into the red: We report a new red-emitting fluorescent viscosity probe suitable for intracellular viscosity imaging of MCF-7 breast cancer cells. This was achieved with the help of DFT calculations that allowed the viscosity sensitivity of the fluorophore to be predicted before synthesis.
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中文翻译:

设计用于细胞内粘度成像的发红光粘度敏感 BODIPY 荧光团

走向红色:我们报告了一种新的发红光的荧光粘度探针,适用于 MCF-7 乳腺癌细胞的细胞内粘度成像。这是在 DFT 计算的帮助下实现的,该计算允许在合成之前预测荧光团的粘度敏感性。
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更新日期:2021-09-22
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