In the article by Leblanc et al., “Transcriptomic Profiling of Canine Atrial Fibrillation Models After One Week of Sustained Arrhythmia,” which published on August 17, 2021, and appeared in the August 2021 issue of the journal (Circulation: Arrhythmia and Electrophysiology. 2021;14:e009887. 10.1161/CIRCEP.120.009887), corrections were needed.

On page 732, the following is incorrect: DE testing was conducted as described above for the 3 groups; no AF (CTL, n=50), AF in sinus rhythm (AF, n=130), and AF in AF rhythm (AF.SR, n=81), with inclusion of sex as a covariate.

This has been corrected to read: DE testing was conducted as described above for the 3 groups; no AF (CTL, n=50), AF in AF rhythm (AF, n=130), and AF in sinus rhythm (AF.SR, n=81), with inclusion of sex as a covariate.

On page 737, the following is incorrect: For differential gene expression analyses, these patients were divided between no AF (n=50), AF in sinus rhythm (n=130), and AF in AF rhythm (n=81). […] We found the strongest overlap between dog AF+AVB and human AF in sinus rhythm, consistent with our hypothesis that earlier stage AF triggers greater gene dysregulation as the cardiac remodeling is ongoing, as opposed to permanent AF.

This has been corrected to read: For differential gene expression analyses, these patients were divided between no AF (n=50), AF in AF rhythm (n=130), and AF in sinus rhythm (n=81). […] We found the strongest overlap between dog AF+AVB and human AF in AF rhythm.

On page 739, the following is incorrect: It is also possible that different transcriptomic programs may be involved at the initiation of arrhythmia and tissue remodeling (AF and AF+AVB dog models) when compared with those dysregulated in the atria once the pathology has been present for years (as is typically the case for human patients from whom atrial samples are obtained).

This has been corrected to read: It is also possible that different transcriptomic programs may be involved at the initiation of arrhythmia and tissue remodeling (AF and AF+AVB dog models) when compared with those dysregulated in the atria once the pathology has been present for years.

Additionally, Figure 5 and Supplemental Table VI were updated.

The authors apologize for these errors.

This correction has been made to the current online version of the article, which is available at https://www.ahajournals.org/doi/10.1161/CIRCEP.120.009887.

在 Leblanc 等人的文章“持续心律失常一周后犬心房颤动模型的转录组学分析”中，该文章于 2021 年 8 月 17 日发表，并出现在 2021 年 8 月的期刊（循环：心律失常和电生理学）上。 2021;14:e009887.10.1161/CIRCEP.120.009887)，需要更正。

在第 732 页上，以下内容是不正确的：DE 测试如上所述对 3 组进行；无 AF（CTL，n=50），窦性心律的 AF（AF，n=130）和 AF 节律的 AF（AF.SR，n=81），包括性别作为协变量。

这已更正为：DE 测试按上述方式对 3 组进行；无 AF（CTL，n=50），AF 节律中的 AF（AF，n=130）和窦性心律中的 AF（AF.SR，n=81），包括性别作为协变量。

在第 737 页上，以下内容是不正确的：对于差异基因表达分析，这些患者被分为无房颤 (n=50)、窦性心律的房颤 (n=130) 和房颤的房颤 (n=81)。[…]我们发现狗 AF+AVB 和人类 AF 在窦性心律中重叠最强烈，这与我们的假设一致，即早期 AF 随着心脏重构的进行而引发更大的基因失调，而不是永久性 AF。

这已更正为：对于差异基因表达分析，将这些患者分为无房颤 (n=50)、房颤心律 (n=130) 和窦性心律房颤 (n=81)。[…] 我们发现狗 AF+AVB 和人类 AF 在 AF 节律上的重叠最强。

在第 739 页上，以下内容是不正确的：与病理学确定后心房失调的转录组程序相比，在心律失常和组织重塑（AF 和 AF+AVB 狗模型）的起始阶段也可能涉及不同的转录组程序存在多年（对于从中获取心房样本的人类患者而言，情况通常如此）。

这已更正为：与心房中的失调相比，心律失常和组织重塑（AF 和 AF+AVB 狗模型）的开始也可能涉及不同的转录组程序。年。

此外，图 5 和补充表 VI 已更新。

作者为这些错误道歉。

此更正已对文章的当前在线版本进行了更正，该版本可在 https://www.ahajournals.org/doi/10.1161/CIRCEP.120.009887 上获得。