Objective

The purpose of this study is to evaluate the effects of combined aerobic and resistance exercise on blood pressure (BP) in postmenopausal women. The results of this study will provide an effective means for postmenopausal women to control BP and reduce the morbidity and mortality of cardiovascular disease (CVD).

Methods

Eligible studies were searched in five electronic databases until November 2020, and 11 randomized controlled trials that met the inclusion criteria were included in this systematic review and meta-analysis. The random-effects model was used to calculate overall effect sizes of weighted mean differences (WMD) and 95% confidence interval (CI). This study was registered in PROSPERO with the registration number: CRD42021225546.

Results

Compared with the control group, the aerobic combined resistance exercise significantly decreased the systolic blood pressure (SBP) and diastolic blood pressure (DBP) by 0.81 mmHg (95% CI, −1.34 to −0.28) and 0.62 mmHg (95% CI, −1.11 to −0.14), respectively. The results of the meta-analysis also indicated that a significant reduction in brachial-to-ankle pulse wave velocity (baPWV) of – 1.18 m/s (95% CI, −1.81 to −0.56) and heart rate (HR) of −0.22 beats/min (95% CI: −0.42 to −0.02) after combined aerobic and resistance exercise intervention. Subgroup analysis showed that postmenopausal women ≥60 years of age who were overweight or had a normal baseline BP were more sensitive to the combined aerobic and resistance exercise. When combined aerobic and resistance exercise frequency < 3 times/week, weekly exercise time ≥ 150 min, or the duration of exercise lasted for 12 weeks, the SBP and DBP of postmenopausal women could be reduced more effectively.

Conclusions

The present study indicates that combined aerobic and resistance exercise can significantly reduce BP in postmenopausal women. Accordingly, combined aerobic and resistance exercise may be an effective way to prevent and manage hypertension in postmenopausal women.

中文翻译：

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有氧运动和抗阻运动对绝经后妇女血压的影响：随机对照试验的系统评价和荟萃分析

客观的

本研究的目的是评估有氧运动和抗阻运动相结合对绝经后妇女血压 (BP) 的影响。本研究的结果将为绝经后妇女控制血压、降低心血管疾病（CVD）的发病率和死亡率提供有效手段。

方法

截至 2020 年 11 月，在五个电子数据库中检索了符合条件的研究，本系统评价和荟萃分析纳入了 11 项符合纳入标准的随机对照试验。随机效应模型用于计算加权平均差 (WMD) 和 95% 置信区间 (CI) 的总体效应大小。本研究在 PROSPERO 注册，注册号：CRD42021225546。

结果

与对照组相比，有氧联合抗阻运动显着降低收缩压（SBP）和舒张压（DBP）0.81 mmHg（95% CI，-1.34至-0.28）和0.62 mmHg（95% CI，-） 1.11 至 -0.14)，分别。荟萃分析的结果还表明，臂至踝脉搏波速度 (baPWV) 显着降低 – 1.18 m/s（95% CI，-1.81 至 -0.56），心率 (HR) 显着降低 - 0.22 次/分钟（95% CI：-0.42 至 -0.02）在联合有氧和抗阻运动干预后。亚组分析显示，年龄≥60 岁的超重或基线血压正常的绝经后女性对有氧运动和抗阻运动相结合更敏感。当有氧和抗阻运动联合频率<3次/周，每周运动时间≥150分钟时，

结论

目前的研究表明，有氧运动和抗阻运动相结合可以显着降低绝经后妇女的血压。因此，结合有氧运动和抗阻运动可能是预防和管理绝经后妇女高血压的有效方法。