It is important to gain insight into the burden of COVID-19 at city district level to develop targeted prevention strategies. We examined COVID-19 related hospitalisations by city district and migration background in the municipality of Amsterdam, the Netherlands. We used surveillance data on all PCR-confirmed SARS-CoV-2 hospitalisations in Amsterdam until 31 May 2020, matched to municipal registration data on migration background. We calculated directly standardised (age, sex) rates (DSR) of hospitalisations, as a proxy of COVID-19 burden, per 100,000 population by city district and migration background. We calculated standardised rate differences (RD) and rate ratios (RR) to compare hospitalisations between city districts of varying socio-economic and health status and between migration backgrounds. We evaluated the effects of city district and migration background on hospitalisation after adjusting for age and sex using Poisson regression. Between 29 February and 31 May 2020, 2326 cases (median age 57 years [IQR = 37–74]) were notified in Amsterdam, of which 596 (25.6%) hospitalisations and 287 (12.3%) deaths. 526/596 (88.2%) hospitalisations could be matched to the registration database. DSR were higher in individuals living in peripheral (South-East/New-West/North) city districts with lower economic and health status, compared to central districts (Centre/West/South/East) (RD = 36.87,95%CI = 25.79–47.96;RR = 1.82,95%CI = 1.65–1.99), and among individuals with a non-Western migration background compared to ethnic-Dutch individuals (RD = 57.05,95%CI = 43.34–70.75; RR = 2.36,95%CI = 2.17–2.54). City district and migration background were independently associated with hospitalisation. City districts with lower economic and health status and those with a non-Western migration background had the highest burden of COVID-19 during the first wave of COVID-19 in Amsterdam.

中文翻译：

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荷兰阿姆斯特丹第一波 COVID-19 期间住院率因城区和种族而异

深入了解市区一级的 COVID-19 负担对于制定有针对性的预防策略非常重要。我们按市区和移民背景检查了荷兰阿姆斯特丹市与 COVID-19 相关的住院情况。我们使用了截至 2020 年 5 月 31 日阿姆斯特丹所有经 PCR 确诊的 SARS-CoV-2 住院的监测数据，并与有关移民背景的市政登记数据相匹配。我们直接计算了按城区和移民背景每 10 万人的标准化（年龄、性别）住院率 (DSR)，作为 COVID-19 负担的代理。我们计算了标准化比率差异（RD）和比率（RR），以比较不同社会经济和健康状况的城市地区之间以及移民背景之间的住院情况。使用泊松回归调整年龄和性别后，我们评估了城市地区和移民背景对住院治疗的影响。2020年2月29日至5月31日期间，阿姆斯特丹通报了2326例病例（中位年龄57岁[IQR = 37-74]），其中596例（25.6%）住院治疗，287例（12.3%）死亡。526/596 (88.2%) 的住院治疗可以与登记数据库相匹配。与中心地区（中部/西部/南部/东部）相比，生活在经济和健康状况较低的外围（东南/新西/北部）城市地区的个体的 DSR 较高（RD = 36.87,95%CI = 25.79–47.96；RR = 1.82，95%CI = 1.65–1.99），以及在具有非西方移民背景的个体与荷兰裔个体之间的比较（RD = 57.05，95%CI = 43.34–70.75；RR = 2.36， 95%CI = 2.17–2.54）。城市地区和移民背景与住院情况独立相关。在阿姆斯特丹的第一波 COVID-19 期间，经济和健康状况较低的城区以及具有非西方移民背景的城区的 COVID-19 负担最高。