Purpose

To identify the predictors of final visual outcome in cases with post-fever retinitis (PFR).

Methods

This is a retrospective study of cases with diagnosis of post-fever retinitis. Colour fundus photograph and optical coherence tomography (OCT) parameters at presentation and final visit were analysed. Various factors at presentation [age, systemic illness, best-corrected visual acuity (BCVA), area of retinitis and hard exudates, OCT parameters], at final visit (OCT parameters) and the treatment modalities used were correlated with BCVA at final visit.

Results

Twenty-four eyes of 16 patients with PFR were included in the study. Median BCVA at presentation was 6/60 and at final visit was 6/9. By multiple linear regression after adjusting for other variables, for every 1 unit increase in height of subretinal fluid (SRF) at fovea at presentation, the value of final BCVA decreased by 0.001 unit. For every 1 unit increase in extent of ellipsoid zone (EZ) loss and subfoveal deposit height, the value of final BCVA decreased by 0.0001 unit and 0.004 unit, respectively. The baseline OCT parameters that had negative correlation with final BCVA included central macular thickness (r: − 0.5182, p: 0.02), maximum SRF height (r: − 0.5539, p < 0.01) and SRF height at fovea (r: − 0.582, p < 0.01). The OCT parameters at final visit which had a negative correlation with final BCVA included disorganisation of retinal inner layers (DRIL) within 1000 microns from centre of fovea (r: − 0.6494, p < 0.01), height of subfoveal deposit (r: − 0.7627, p < 0.01), horizontal extent of subfoveal deposit (r: − 0.6695, p < 0.01) and extent of EZ loss (r: − 0.8216, p < 0.01).

Conclusion

Height of SRF at presentation, extent of EZ loss and subfoveal deposit height at final visit were associated with poor final BCVA in PFR.

中文翻译：

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发热后视网膜炎视觉结果的预测因素：回顾性分析

目的

确定发热后视网膜炎 (PFR) 患者最终视力结果的预测因素。

方法

这是一项对诊断为发热后视网膜炎的病例的回顾性研究。分析了演示和最终访问时的彩色眼底照片和光学相干断层扫描 (OCT) 参数。就诊时的各种因素 [年龄、全身性疾病、最佳矫正视力 (BCVA)、视网膜炎面积和硬性渗出液、OCT 参数]、最终访问时（OCT 参数）和使用的治疗方式与最终访问时的 BCVA 相关。

结果

该研究包括 16 名 PFR 患者的 24 只眼。就诊时的 BCVA 中位数为 6/60，最终访视时为 6/9。通过调整其他变量后的多元线性回归，就诊时中央凹视网膜下液（SRF）高度每增加1个单位，最终BCVA值下降0.001个单位。椭球区 (EZ) 损失范围和中心凹下沉积高度每增加 1 个单位，最终 BCVA 的值分别减少 0.0001 个单位和 0.004 个单位。与最终 BCVA 呈负相关的基线 OCT 参数包括中心黄斑厚度 ( r : − 0.5182, p : 0.02)、最大 SRF 高度 ( r : − 0.5539, p  < 0.01) 和中央凹处的 SRF 高度 ( r: - 0.582, p  < 0.01)。最终访视时与最终 BCVA 呈负相关的 OCT 参数包括距中央凹中心 1000 微米以内的视网膜内层 (DRIL) 解体 ( r : − 0.6494, p  < 0.01)、中央凹下沉积物的高度 ( r : − 0.7627 , p  < 0.01)、中心凹下沉积物的水平范围 ( r : − 0.6695, p  < 0.01) 和 EZ 损失的范围 ( r : − 0.8216, p  < 0.01)。

结论

就诊时 SRF 的高度、EZ 损失的程度和最终访视时的中央凹下沉积高度与 PFR 中较差的最终 BCVA 相关。