BACKGROUND In primary care (PC) many patients suffer from multimorbidity involving depression and/or anxiety. Collaborative care (CC) has shown promising results for patients with depression, anxiety, and multimorbidity involving depression. However, specific content in CC for patients with multimorbidity involving depression and/or anxiety is unknown. OBJECTIVE (i) To examine the effect of CC interventions in patients with multimorbidity involving depression and/or anxiety compared with usual care; (ii) to identify specific content of CC. METHODS We conducted a systematic literature review of randomized controlled trial studies evaluating CC models for adults with multimorbidity involving depression and/or anxiety in PC settings. PubMed, CINAHL, Web of Science, and PsycInfo were searched in December 2019. We conducted a qualitative synthesis using an existing framework and developed a new framework to map the content for each studied intervention. RESULTS We identified 1,447 studies. Twelve publications were included. Eleven had medium-to-high quality of CC for patients with multimorbidity involving depression. Specific content of CC in these studies is: A stepped care model, involving medication and psychotherapy delivered by a nurse or psychologist Care Manager (CM) focusing on problem-solving techniques; follow-up including monitoring of symptoms and function, and relapse prevention strategies; scheduled CM supervision. CONCLUSIONS Specific content for CC for patients with multimorbidity involving depression is identified from current research. Research gaps were found regarding CC for patients with multimorbidity and anxiety, depression and anxiety, and depression and/or anxiety and more than 2 diseases.

中文翻译：

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协作护理的具体内容：对初级保健中涉及抑郁和/或焦虑的多病患者的协作护理干预的系统评价。

背景技术在初级保健（PC）中，许多患者患有涉及抑郁和/或焦虑的多种疾病。协作护理 (CC) 对患有抑郁症、焦虑症和涉及抑郁症的多种疾病的患者显示出可喜的结果。然而，对于涉及抑郁和/或焦虑的多病患者，CC 中的具体内容尚不清楚。目标 (i) 与常规护理相比，检查 CC 干预对抑郁和/或焦虑的多发病患者的影响；(ii) 确定抄送的具体内容。方法 我们对随机对照试验研究进行了系统的文献回顾，该研究评估了在 PC 环境中患有包括抑郁和/或焦虑的多种疾病的成人的 CC 模型。PubMed、CINAHL、Web of Science 和 PsycInfo 于 2019 年 12 月进行了检索。我们使用现有框架进行了定性综合，并开发了一个新框架来绘制每个研究干预的内容。结果 我们确定了 1,447 项研究。包括十二份出版物。对于患有抑郁症的多病患者，11 名患者的 CC 质量为中至高质量。这些研究中 CC 的具体内容是： 阶梯式护理模式，包括由护士或心理学家提供的药物和心理治疗 护理经理 (CM) 专注于解决问题的技巧；随访，包括监测症状和功能，以及预防复发的策略；预定的CM监督。结论 从目前的研究中确定了针对患有抑郁症的多种疾病患者的 CC 的具体内容。在患有多病和焦虑症的患者中发现了关于 CC 的研究空白，