Notch signaling pathway, known to influence bone resorption in several oral diseases, has not been analyzed in peri-implantitis yet. Therefore, the aims of the present study were to determine the levels of Notch cascade, bone remodeling mediators, and pro-inflammatory cytokines, in conjunction with clinical parameters, in subjects with peri-implant mucositis and peri-implantitis.

中文翻译：

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Notch 下调和炎性细胞因子和 RANKL 过表达参与种植体周围粘膜炎和种植体周围炎：一项横断面研究

Notch 信号通路，已知在几种口腔疾病中影响骨吸收，尚未在种植体周围炎中进行分析。因此，本研究的目的是结合临床参数确定种植体周围粘膜炎和种植体周围炎患者的 Notch 级联、骨重塑介质和促炎细胞因子的水平。