Cubosome Based Ion-Selective Optodes–Toward Tunable Biocompatible Sensors,Analytical Chemistry

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Cubosome Based Ion-Selective Optodes–Toward Tunable Biocompatible Sensors
Analytical Chemistry ( IF 6.7 ) Pub Date : 2021-09-21 , DOI: 10.1021/acs.analchem.1c01247
Emilia Stelmach ₁ , Ewa Nazaruk ₁ , Krzysztof Maksymiuk ₁ , Agata Michalska ₁

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We report here on a new generation of optical ion-selective sensors benefiting from cubosomes or hexosomes–nanostructural lipid liquid phase. Cubosome as well as hexosome optodes offer biocompatibility, self-assembly preparation, high stability in solution, and unique, tunable analytical performance. The temperature trigger reversibly changes the lipid nanoparticle internal structure–changing analyte access to the bulk of the probe and ultimately affecting the response pattern. Thus, cubosome or hexosome optodes are highly promising alternatives to conventional polymeric based optical nanoprobes.

中文翻译：

基于立方体的离子选择性光电器件——面向可调谐生物相容性传感器

我们在此报告了受益于立方体或六糖体-纳米结构脂质液相的新一代光学离子选择性传感器。立方体和六体光极提供生物相容性、自组装制备、溶液的高稳定性以及独特的、可调节的分析性能。温度触发器可逆地改变脂质纳米颗粒的内部结构，从而改变分析物与探针主体的接触，并最终影响响应模式。因此，立方体或六体光极是传统基于聚合物的光学纳米探针的非常有前途的替代品。

更新日期：2021-10-06

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