Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion,Cell Proliferation

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Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-09-21 , DOI: 10.1111/cpr.13125
Lili Du _{1,

2,

3} , Wenbo Deng _{4,

5} , Shanshan Zeng ₁ , Pei Xu ₁ , Lijun Huang ₁ , Yingyu Liang ₁ , Yang Wang _{4,

5} , Hui Xu _{4,

5} , Jingman Tang ₁ , Shilei Bi ₁ , Lizi Zhang ₆ , Yulian Li ₁ , Luwen Ren ₁ , Lin Lin ₁ , Weinan Deng ₁ , Mingxing Liu ₁ , Jingsi Chen _{1,

2,

3} , Haibin Wang _{4,

5} , Dunjin Chen _{1,

2,

3}

Affiliation

Successful pregnancy involves the homeostasis between maternal decidua and fetoplacental units, whose disruption contributes to compromised pregnancy outcomes, including recurrent spontaneous abortion (RSA). The role of cell heterogeneity of maternal decidua in RSA is yet to be illustrated.

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