Esophageal metastasis of renal cell carcinoma (RCC) is extremely rare. We have described herein a case of a 59-year-old man with esophageal metastasis of RCC that was endoscopically resected. The case was a 59-year-old man who had undergone left nephrectomy for renal clear cell carcinoma 17 years ago and splenectomy for splenic metastasis 3 years ago. Esophagogastroduodenoscopy (EGD) performed 9 years ago revealed a small reddish elevated lesion with a smooth surface in the middle esophagus; this lesion increased in size 4 years ago. However, no biopsy was performed. The lesion continued to grow in size and was found to have become nodular during the present observation. Biopsy revealed clear cell carcinoma. Endoscopic ultrasound (EUS) revealed that the lesion had not invaded the submucosa, and contrast-enhanced computed tomography did not reveal any other metastasis. The lesion was successfully removed en bloc via endoscopic submucosal dissection (ESD). Pathologically, the tumor was detected in the subepithelium with focal infiltration of the muscularis mucosa. It consisted of monotonous cells with small nuclei and a clear cytoplasm. Immunohistological findings indicated that the tumor was a metastasis of RCC. The lateral and vertical margins were noted to be free. We have presented herein a case of esophageal metastasis of RCC that had progressed over 9 years and was then resected en bloc through endoscopic submucosal dissection.

中文翻译：

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内镜黏膜下剥离术切除肾细胞癌食管转移1例报告

肾细胞癌 (RCC) 的食管转移极为罕见。我们在本文中描述了一例 59 岁男性，患有 RCC 食管转移，经内镜切除。病例为59岁男性，17年前因肾透明细胞癌行左肾切除术，3年前因脾转移行脾切除术。9 年前进行的食管胃十二指肠镜检查 (EGD) 显示中段食管有一个表面光滑的红色小病灶；这个病灶在 4 年前增大了。然而，没有进行活检。在目前的观察中，病变继续扩大，并发现已变成结节。活检显示透明细胞癌。超声内镜（EUS）显示病变未侵犯黏膜下层，对比增强计算机断层扫描未发现任何其他转移。通过内窥镜黏膜下剥离术 (ESD) 成功地整块切除了病变。病理上，在上皮下组织中检测到肿瘤，粘膜肌层有局灶性浸润。它由具有小细胞核和透明细胞质的单调细胞组成。免疫组织学结果表明肿瘤是 RCC 的转移。注意到横向和纵向边缘是游离的。我们在此介绍了一例 RCC 食管转移病例，该病例进展超过 9 年，然后通过内窥镜黏膜下剥离术整块切除。在上皮下组织中检测到肿瘤，黏膜肌层有局灶性浸润。它由具有小细胞核和透明细胞质的单调细胞组成。免疫组织学结果表明肿瘤是 RCC 的转移。注意到横向和纵向边缘是游离的。我们在此介绍了一例 RCC 食管转移病例，该病例进展超过 9 年，然后通过内窥镜黏膜下剥离术整块切除。在上皮下组织中检测到肿瘤，黏膜肌层有局灶性浸润。它由具有小细胞核和透明细胞质的单调细胞组成。免疫组织学结果表明肿瘤是 RCC 的转移。注意到横向和纵向边缘是游离的。我们在此介绍了一例 RCC 食管转移病例，该病例进展超过 9 年，然后通过内窥镜黏膜下剥离术整块切除。