Natural polysaccharides and their designed structures are extremely valuable due to their intrinsic pharmacological properties and are also used as pharmaceutical aids. These naturally occurring polysaccharides (e.g., psyllium and alginate) are gaining popularity for their use in the preparation of interpenetrating polymer network (IPN) materials with improved swelling ability, biodegradability, stability, non-cytotoxic, biocompatibility, and cost-effectiveness. IPN is prepared sequentially or simultaneously by microwave irradiation, casting evaporation, emulsification cross-linking, miniemulsion/inverse miniemulsion technique, and radiation polymerization methods. In addition, the prepared IPNs have has been extensively characterized using various analytical and imaging techniques before sustainable deployment for multiple applications. Regardless of these multi-characteristic attributes, the current literature lacks a detailed overview of the biomedical aspects of psyllium, alginate, and their engineered IPN structures. Herein, we highlight the unique synthesis, structural, and biomedical considerations of psyllium, alginate, and engineered IPN structures. In this review, a wide range of biomedical applications, such as role as a drug carrier for sustain delivery, wound dressing, tissue engineering, and related miscellaneous application of psyllium, alginate, and their IPN structures described with appropriate examples. Further research will be carried out for the development of IPN using psyllium and alginate, which will be a smart and active carrier for drugs used in the treatment of life-threatening diseases due to their inherent pharmacological potential such as hypoglycemic, immunomodulatory, antineoplastic, and antimicrobial.

天然多糖及其设计的结构由于其固有的药理特性而极具价值，也可用作药物助剂。这些天然存在的多糖（例如车前草和藻酸盐）因其在制备互穿聚合物网络 (IPN) 材料中的用途而越来越受欢迎，这些材料具有改进的溶胀能力、生物降解性、稳定性、无细胞毒性、生物相容性和成本效益。IPN 通过微波辐射、浇铸蒸发、乳化交联、细乳液/反细乳液技术和辐射聚合方法依次或同时制备。此外，在可持续部署用于多种应用之前，已使用各种分析和成像技术对制备的 IPN 进行了广泛表征。不管这些多特征属性如何，当前的文献缺乏对车前子、藻酸盐及其工程化 IPN 结构的生物医学方面的详细概述。在此，我们重点介绍了车前草、藻酸盐和工程化 IPN 结构的独特合成、结构和生物医学考虑。在这篇综述中，广泛的生物医学应用，例如作为药物载体用于持续递送、伤口敷料、组织工程，以及车前草、藻酸盐及其 IPN 结构的相关杂项应用，并用适当的例子进行了描述。将进一步研究使用车前草和海藻酸盐开发 IPN，