The ASCIZ-DYNLL1 axis is essential for TLR4-mediated antibody responses and NF-κB pathway activation,Molecular and Cellular Biology

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The ASCIZ-DYNLL1 axis is essential for TLR4-mediated antibody responses and NF-κB pathway activation
Molecular and Cellular Biology ( IF 3.2 ) Pub Date : 2021-09-20 , DOI: 10.1128/mcb.00251-21
Rui Liu ₁ , Ashleigh King ₁ , David Tarlinton ₂ , Jörg Heierhorst _{1,

3}

Affiliation

Toll-like receptors (TLRs) and IL-1 receptors regulate immune and inflammatory responses by activating the nuclear factor (NF)-κB pathway. Here we report that B cell-specific loss of Dynein light chain-1 (DYNLL1, LC8) or its designated transcription ...

中文翻译：

ASCIZ-DYNLL1 轴对于 TLR4 介导的抗体反应和 NF-κB 通路激活至关重要

Toll 样受体 (TLR) 和 IL-1 受体通过激活核因子 (NF)-κB 通路来调节免疫和炎症反应。在这里，我们报告 B 细胞特异性失去动力蛋白轻链 1 (DYNLL1、LC8) 或其指定的转录...

更新日期：2021-09-21

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