当前位置: X-MOL 学术Antimicrob. Agents Chemother. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Intracellular activity of antibiotics against Coxiella burnetii in a model of activated human THP-1 cells
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-09-20 , DOI: 10.1128/aac.01061-21
Frédéric Peyrusson 1 , Adam O Whelan 2 , Margaret G Hartley 2 , Isobel H Norville 2 , Sarah V Harding 2 , Françoise Van Bambeke 1
Affiliation  

We evaluated antibiotic activity against the intracellular bacterium Coxiella burnetii using an activated THP-1 cell model of infection. At clinically-relevant concentrations, the intracellular bacterial load was reduced 300-fold by levofloxacin and ...

中文翻译:

在活化的人 THP-1 细胞模型中抗生素对伯内氏柯克氏菌的细胞内活性

我们使用激活的 THP-1 细胞感染模型评估了针对细胞内细菌伯氏柯氏杆菌的抗生素活性。在临床相关浓度下,左氧氟沙星和 ...
更新日期:2021-09-21
down
wechat
bug