Background: The medical fascination with the appendix vermiformis dates from the clandestine prosectors of the fifteenth century. The surgical management of appendiceal inflammation dates from 1735, but acceptance that acute appendicitis (AA) should be treated primarily by resection with or without drainage would not follow for 150 years. Recent publication of several randomized clinical trials (RCTs) of non-operative management (NOM) of AA affords the opportunity to review the historical record, describe the evolution of AA management toward NOM, and assess what is in the best interest of the patient.

中文翻译：

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阑尾炎的非手术治疗：进化，而不是革命

背景：对蠕形阑尾的医学迷恋可以追溯到十五世纪的秘密检察官。阑尾炎症的手术治疗可追溯到 1735 年，但接受急性阑尾炎 (AA) 应主要通过切除术伴或不伴引流术治疗的观点在 150 年之后并未得到认可。最近发表的几项 AA 非手术管理 (NOM) 的随机临床试验 (RCT) 提供了回顾历史记录、描述 AA 管理向 NOM 的演变以及评估什么最符合患者利益的机会。