Dipeptedyl peptidase-4 (DPP-4) inhibitor downregulates HMGB1/TLR4/NF-κB signaling pathway in a diabetic rat model of non-alcoholic fatty liver disease,Archives of Physiology and Biochemistry

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Dipeptedyl peptidase-4 (DPP-4) inhibitor downregulates HMGB1/TLR4/NF-κB signaling pathway in a diabetic rat model of non-alcoholic fatty liver disease
Archives of Physiology and Biochemistry ( IF 2.5 ) Pub Date : 2021-09-20 , DOI: 10.1080/13813455.2021.1975758
Mona M Allam ₁ , Reham M Ibrahim ₁ , Walaa Bayoumie El Gazzar _{2,

3} , Mona A Said ₁

Affiliation

Inflammatory and immune pathways play a crucial role in the pathophysiology of non-alcoholic fatty liver disease (NAFLD). Sitagliptin blocks the dipeptidyl peptidase-4 (DPP-4) enzyme, mechanisms th...

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