A new electrochemical sensor based on Li₂FeMn₃O₈/C–C₃N₄ (LFMO/CCN)/1-ethyl-3-methylimidazolium chloride modified carbon paste electrode (CPE) has been constructed to measure pantoprazole sodium (PNZS). The electrochemical impedance spectroscopy (EIS) method was employed to evaluate the electrode charge-transfer resistances. Moreover, the differential pulse voltammetry method was used to detect PNZS in phosphate buffer solution (PBS) at pH 7.0. The detection limit of 80.0 × 10⁻⁹ M and 10.9 × 10⁻⁷ M was obtained under optimal conditions in the linear concentration range of PNZS 0.09–100 μM and 100–900 μM. Chronoampermetry technique was utilized to determine the diffusion coefficient (D) of PNZS on the modified electrode surface. The CCN/LFMO/IL/CPE was successfully used to determine PNZS in various drug formulations such as tablets and vials. Finally, simultaneous determination of PNZS and acetaminophen was accomplished with no interference based on the proposed sensor.

构建了一种基于 Li ₂ FeMn ₃ O ₈ /C–C ₃ N ₄ (LFMO/CCN)/1-乙基-3-甲基咪唑氯化物改性碳糊电极 (CPE)的新型电化学传感器来测量泮托拉唑钠 (PNZS) . 采用电化学阻抗谱（EIS）方法来评估电极电荷转移电阻。此外，差分脉冲伏安法用于检测 pH 7.0 的磷酸盐缓冲溶液 (PBS) 中的 PNZS。80.0 × 10 ^-9  M 和 10.9 × 10 ^-7的检出限 M 是在 PNZS 0.09–100 μM 和 100–900 μM 的线性浓度范围内的最佳条件下获得的。计时电流法技术用于确定 PNZS 在改性电极表面上的扩散系数 (D)。CCN/LFMO/IL/CPE 已成功用于测定各种药物制剂（如片剂和小瓶）中的 PNZS。最后，基于所提出的传感器，在没有干扰的情况下同时测定了 PNZS 和对乙酰氨基酚。