Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials talks to Pieter Cullis about the history and future of lipid nanoparticle–nucleic acid drugs.

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从脂质到脂质纳米颗粒再到 mRNA 疫苗

脂质纳米颗粒对 mRNA 疫苗至关重要。40 多年前，不列颠哥伦比亚大学教授 Pieter Cullis 的实验室奠定了基于脂质的药物输送系统的基础。Nature Reviews Materials 与 Pieter Cullis 讨论脂质纳米颗粒核酸药物的历史和未来。