Methods for the direct one-step replacement of a hydrogen atom in a C–H bond by an organic functional group can create enormous possibilities for synthetic applications. On the way to solve this challenge, the discovery of the reaction of organopalladium complexes with olefins opened a new era in catalysis and organic chemistry.

中文翻译：

---

交叉耦合的曙光

用有机官能团直接一步替换 C-H 键中的氢原子的方法可以为合成应用创造巨大的可能性。在解决这一挑战的过程中，有机钯配合物与烯烃反应的发现开启了催化和有机化学的新纪元。