NASH, which is a common clinical condition predisposing to advanced liver diseases, has become a worldwide epidemic. A large and growing unmet therapeutic need for this condition reflects incomplete understanding of its pathogenesis. In the current study, we identified a transcription factor, zinc fingers and homeoboxes 2 (ZHX2), in hepatocytes as a protective factor against steatohepatitis.

中文翻译：

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转录因子锌指和同源框 2 通过磷酸酶和张力蛋白同系物的转录激活减轻 NASH

NASH 是一种易患晚期肝病的常见临床病症，已成为全球流行病。对这种情况的巨大且不断增长的未满足治疗需求反映了对其发病机制的不完全理解。在当前的研究中，我们鉴定了肝细胞中的转录因子锌指和同源框 2 (ZHX2) 作为抗脂肪性肝炎的保护因子。