Objective. The aim of this study was to investigate the relationship between different psoriasis types and thyroid dysfunction. Methods. The data of patients diagnosed with psoriasis between January 2013 and October 2018 who underwent thyroid function tests were collected. Free triiodothyronine (FT3), free thyroxine (FT4), total triiodothyronine (TT3), total thyroxine (TT4), thyroid-stimulating hormone (TSH), thyroglobulin antibody (TGAb), and thyroid peroxidase antibody (TPOAb) were measured. The thyroid function of patients with psoriasis vulgaris, pustular psoriasis, erythrodermic psoriasis, and psoriatic arthritis was evaluated, and the differences in hormone levels and antibodies in the pituitary-thyroid axis with psoriasis type were analyzed. Results. The data of a total of 468 patients were analyzed in this study. The proportion of normal hormone levels was higher among vulgaris patients (), while the erythrodermic patients were more likely to have decreased FT3 or FT4 but normal TSH (). FT3 levels were lower in pustular patients (), FT4 levels were lower in erythrodermic patients (), and TSH levels were higher in patients with psoriatic arthritis (). TPOAb levels were higher than normal in all patients, but there was no significant difference in the levels of TPOAb and TGAb among 4 types of the patients. Conclusion. Psoriasis is related to thyroid dysfunction, especially in patients with atypical psoriasis types. The possibility of complications should be considered in erythrodermic patients.

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不同银屑病类型与甲状腺功能障碍的关系：回顾性分析

客观。本研究的目的是调查不同类型的银屑病与甲状腺功能障碍之间的关系。方法。收集 2013 年 1 月至 2018 年 10 月期间诊断为银屑病的患者接受甲状腺功能检查的数据。测量游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、总三碘甲状腺原氨酸（TT3）、总甲状腺素（TT4）、促甲状腺激素（TSH）、甲状腺球蛋白抗体（TGAb）和甲状腺过氧化物酶抗体（TPOAb）。对寻常型银屑病、脓疱型银屑病、红皮病型银屑病、银屑病关节炎患者的甲状腺功能进行评价，分析不同银屑病类型的垂体-甲状腺轴激素水平和抗体的差异。结果. 本研究共分析了 468 例患者的数据。寻常型患者激素水平正常的比例较高（），而红皮病患者更可能有 FT3 或 FT4 降低但 TSH 正常（）。脓疱患者的 FT3 水平较低（），红皮病患者的 FT4 水平较低（），而银屑病关节炎患者的 TSH 水平较高（）。所有患者TPOAb水平均高于正常水平，但4类患者TPOAb和TGAb水平差异无统计学意义。结论。银屑病与甲状腺功能障碍有关，尤其是在非典型银屑病类型的患者中。红皮病患者应考虑并发症的可能性。