Rhizoma Paridis, the rhizome of liliaceous plants Paris polyphylla, is one of the most commonly used herbal drugs in China. Phytochemical and pharmacological studies have shown that steroid saponins were the major effective ingredients of Rhizoma Paridis to exert antitumor, anti-inflammatory, hemostasis, and antifibrosis functions. In this review, we discussed the chemical structures of steroid saponins and their related biological activity and mechanisms in cellular and animal models, aiming to provide a reference for future comprehensive exploitation and development of saponins.

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白花根甾体皂苷的化学成分及药理作用

白头翁是百合科植物多叶的根茎，是我国最常用的中草药之一。植物化学和药理研究表明，甾体皂苷是白芷发挥抗肿瘤、抗炎、止血、抗纤维化作用的主要有效成分。在这篇综述中，我们讨论了类固醇皂苷的化学结构及其在细胞和动物模型中的相关生物学活性和机制，旨在为未来皂苷的综合开发和开发提供参考。