A silk fibroin silicon-based composite aerogel (SSA) has been modified via a SuFEx reaction for application in the adsorption of anionic pollutants and antimicrobials in water. The tyrosine fragment in the silk fibroin was modified by a high yielding SuFEx click reaction. A quaternary ammonium salt functionality was introduced into the silk fibroin protein and the modified silk fibroin protein was crosslinked with tetraethyl orthosilicate. The aerogel was then prepared by freeze-drying. The aerogel obtained has biocompatibility and biodegradability properties. Four types of dyes (Methyl orange, Rhodamine B, Methylene blue and Acid red) were applied as targets and the saturated adsorption amounts were calculated. The adsorption behavior of the dyes towards SSA was studied by fitting Langmuir and Freundlich adsorption models. A pseudo-first order kinetic model and a pseudo-second order kinetic model were used to study the kinetics of the adsorption process. After 6 cycles, the removal rate of methyl orange by SSA remained at 81.25%. The adsorption capacity and anti-interference ability of SSA on some other polluting anions such as PO₄³⁻ and CrO₄²⁻ were also measured and the efficiency adsorption reached up to 70.94% and 77.91%, respectively. The antibacterial effect of SSA was evaluated with Escherichia coli and Staphylococcus aureus as representative examples.

丝素蛋白硅基复合气凝胶 (SSA) 已通过 SuFEx 反应改性，用于吸附水中的阴离子污染物和抗菌剂。丝素蛋白中的酪氨酸片段通过高产 SuFEx 点击反应进行了修饰。将季铵盐官能团引入丝素蛋白中，并将改性丝素蛋白与原硅酸四乙酯交联。然后通过冷冻干燥制备气凝胶。获得的气凝胶具有生物相容性和生物降解性。以四种染料（甲基橙、罗丹明B、亚甲蓝和酸性红）为目标，计算饱和吸附量。通过拟合 Langmuir 和 Freundlich 吸附模型研究染料对 SSA 的吸附行为。拟一级动力学模型和拟二级动力学模型用于研究吸附过程的动力学。6个循环后，SSA对甲基橙的去除率保持在81.25%。SSA对PO等其他污染阴离子的吸附能力和抗干扰能力还测量了₄ ^3-和 CrO ₄ ^2-，吸附效率分别达到了 70.94% 和 77.91%。以大肠杆菌和金黄色葡萄球菌为代表，评价了SSA的抗菌效果。