The aim of this article was to evaluate the clinical and laboratory profile of people with oral Kaposi's sarcoma (KS) associated with AIDS (KS-AIDS), followed-up at a public university hospital in Salvador, Bahia, Brazil, in the past 10 years. We identified patients diagnosed with KS-AIDS, presenting oral manifestation from January 2007 to December 2017. We searched, in the hospital information systems, the patient demographics, diagnostic data, treatment, image studies, and oral photographic records. Of the 39 cases of KS-AIDS identified at the institution, 14 (22.8%) presented oral lesions. There was a predominance of black men, with a mean age of 32.5 years. Most cases (85.1%) manifested signs of KS simultaneously with the diagnosis of HIV infection, with extremely low initial CD4 T cell counts (average of 52.6 cells/mm²) and visceral involvement (64.3%). The palate (32.1%) and gingiva (21.4%) were the most affected oral sites. Histologically, the tumors exhibited proliferation of spindle cells between vascular clefts and extravasated erythrocytes. Oral KS-AIDS was frequent in young black adult men, with severe immunosuppression and high viral load counting, mostly with lesions manifested in the same period of diagnosis of infection by the HIV.

中文翻译：

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HIV/AIDS 患者口腔卡波西肉瘤的临床和实验室概况

本文的目的是评估过去 10 年在巴西巴伊亚州萨尔瓦多的公立大学医院随访的与 AIDS (KS-AIDS) 相关的口腔卡波西肉瘤 (KS) 患者的临床和实验室特征。年。我们确定了 2007 年 1 月至 2017 年 12 月期间出现口腔表现的 KS-AIDS 患者。我们在医院信息系统中搜索了患者的人口统计学、诊断数据、治疗、图像研究和口腔摄影记录。在该机构确定的 39 例 KS-AIDS 中，14 例 (22.8%) 出现口腔病变。黑人男性占主导地位，平均年龄为 32.5 岁。大多数病例 (85.1%) 在诊断 HIV 感染的同时表现出 KS 体征，初始 CD4 T 细胞计数极低（平均 52.6 个细胞/毫米²）和内脏受累（64.3%）。上颚 (32.1%) 和牙龈 (21.4%) 是受影响最大的口腔部位。组织学上，肿瘤表现出血管裂隙和外渗红细胞之间梭形细胞的增殖。口腔KS-AIDS在年轻的黑人成年男性中很常见，免疫抑制严重，病毒载量计数高，大多在诊断为HIV感染的同一时期出现病变。