Background

Lower socioeconomic position usually portends worse health outcomes, but multiple studies have found that atopic dermatitis is associated with higher socioeconomic position, but the nature of this relationship remains unclear.

Objective

To systematically review the literature on socioeconomic position and atopic dermatitis and determine if the association varies by patient or study characteristics.

Methods

A literature search was conducted in the PubMed and Embase databases. Individual-level studies addressing the association between all measures of socioeconomic position and the prevalence or incidence of atopic dermatitis were eligible for inclusion. Two independent reviewers screened all texts and extracted all data for qualitative synthesis.

Results

88 studies met inclusion criteria. Overall, 42% (37/88) of studies found atopic dermatitis to be positively associated with socioeconomic position, 15% (13/88) found a negative association, and 43% (38/88) found a null or inconsistent association. Studies conducted in Europe, among children, and based on self-report of eczema were more likely to find a positive association with socioeconomic position.

Limitations

Studies varied both in terms of measurement of socioeconomic position and definition of atopic dermatitis, limiting quantitative synthesis.

Conclusion

There is not consistent evidence of a positive association between atopic dermatitis and socioeconomic position.

中文翻译：

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社会经济地位与特应性皮炎之间关系的混合证据：系统评价

背景

较低的社会经济地位通常预示着较差的健康结果，但多项研究发现，特应性皮炎与较高的社会经济地位相关，但这种关系的性质仍不清楚。

客观的

系统回顾关于社会经济地位和特应性皮炎的文献，并确定相关性是否因患者或研究特征而异。

方法

在 PubMed 和 Embase 数据库中进行了文献检索。涉及所有社会经济地位测量与特应性皮炎患病率或发病率之间关联的个体水平研究符合纳入标准。两名独立审稿人筛选所有文本并提取所有数据以进行定性综合。

结果

88 项研究符合纳入标准。总体而言，42% (37/88) 的研究发现特应性皮炎与社会经济地位呈正相关，15% (13/88) 发现负相关，43% (38/88) 发现无关联或不一致。在欧洲进行的儿童研究，基于湿疹的自我报告，更有可能发现与社会经济地位呈正相关。

限制

研究在社会经济地位的衡量和特应性皮炎的定义方面各不相同，限制了定量综合。

结论

没有一致的证据表明特应性皮炎与社会经济地位之间存在正相关。