We present the case of a 13-year-old male with a complex congenital cardiac history who was supported with extracorporeal membrane oxygenation for 394 days while awaiting cardiac transplantation. The patient underwent successful cardiac transplantation after 394 days of support with veno-arterial extracorporeal membrane oxygenation and is currently alive 2 years after cardiac transplantation. We believe that this case represents the longest period of time that a patient has been supported with extracorporeal membrane oxygenation as a bridge to cardiac transplantation.We also review the literature associated with prolonged support with extracorporeal membrane oxygenation. This case report documents many of the challenges associated with prolonged support with extracorporeal membrane oxygenation, including polymicrobial bacterial and fungal infections, as well as renal dysfunction. It is possible to successfully bridge a patient to cardiac transplantation with prolonged support with extracorporeal membrane oxygenation of over 1 year; however, multidisciplinary collaboration is critical.

中文翻译：

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支持体外膜肺氧合超过 1 年作为心脏移植的桥梁：病例报告和文献回顾

我们介绍了一名 13 岁男性的病例，他有复杂的先天性心脏病史，在等待心脏移植期间接受体外膜肺氧合 394 天。该患者在静脉-动脉体外膜肺氧合支持 394 天后成功进行了心脏移植，目前在心脏移植后 2 年仍存活。我们认为，该病例代表了患者接受体外膜肺氧合作为心脏移植桥梁的最长支持时间。我们还回顾了与长期支持体外膜肺氧合相关的文献。本病例报告记录了与长期支持体外膜氧合相关的许多挑战，包括多种微生物细菌和真菌感染，以及肾功能不全。通过体外膜氧合超过 1 年的长期支持，有可能成功地将患者过渡到心脏移植；然而，多学科合作至关重要。