In his Target Article, Deacon develops simple models that assist in understanding the role of RNA in the origins of life. However, his models fail to adequately represent an important evolutionary dynamic. Central to this dynamic is the selection that impinges on RNA molecules in the context of their association with proto-metabolisms. This selection shapes the role of RNA in the emergence of life. When this evolutionary dynamic is appropriately taken into account, it predicts a role for RNA that is consistent with the Managed-Metabolism Hypothesis about the origins of life, and inconsistent with Deacon’s account.

中文翻译：

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RNA 在生命起源中的作用：代理“管理者”，还是“卸载”约束的接受者？

在他的目标文章中，Deacon 开发了一些简单的模型来帮助理解 RNA 在生命起源中的作用。然而，他的模型未能充分代表一个重要的进化动态。这种动态的核心是在 RNA 分子与原代谢相关的背景下影响它们的选择。这种选择塑造了 RNA 在生命出现中的作用。当适当考虑到这种进化动态时，它预测了 RNA 的作用，它与关于生命起源的管理代谢假说一致，但与 Deacon 的解释不一致。