The utilization and applications of biopolymer based electrospun matrices has expanded in various fields because of their advantageous features, however due to the poor mechanical strength their true potential has still not been realized. Enhancing mechanical strength of electrospun matrices is a long sought-after goal which is achieved by maximizing the interactions in inclusion complex (IC) of poly(ɛ-caprolactone) (PCL) with urea, in this work. The ratio of urea was varied with respect to PCL and changes in the enthalpy of fusion (ΔH_f) for IC thus formed were analyzed using DSC. Binding efficiency (BE) of PCL and urea within the IC was calculated using ΔH_f, which was reproducibly altered by varying urea to PCL ratio. The extent of hydrogen bonding between PCL and urea, varied in this way, was also confirmed by FTIR and XRD analysis. PCL and urea-based IC samples were electrospun to fabricate uniform fibrous matrices which upon selective removal of urea showed superior mechanical strength as compared to neat PCL matrix. The crystallinity of coalesced PCL was found to be significantly enhanced, up to 34%, in IC with urea as a result of better orientation of PCL chains. A memory effect on crystallization was ultimately seen where characteristics of coalesced PCL matrix were found to be retained even after dissolution of matrix in acetic acid and electrospinning it again.

基于生物聚合物的电纺基质因其优越的特性而在各个领域的利用和应用得到了扩展，但由于机械强度差，其真正的潜力仍未得到发挥。在这项工作中，提高电纺基质的机械强度是一个长期追捧的目标，通过最大化聚（ɛ-己内酯）（PCL）与尿素的包合物（IC）中的相互作用来实现。尿素的比率相对于PCL而变化，并且使用DSC分析由此形成的IC的熔化焓( ΔH _f )的变化。使用ΔH _f计算 IC 内 PCL 和尿素的结合效率 (BE)，通过改变尿素与 PCL 的比率可重复地改变。PCL 和尿素之间的氢键程度以这种方式变化，也通过 FTIR 和 XRD 分析得到证实。PCL 和基于尿素的 IC 样品被静电纺丝以制造均匀的纤维基质，与纯 PCL 基质相比，该基质在选择性去除尿素后显示出优异的机械强度。发现聚结的 PCL 的结晶度在含有尿素的 IC 中显着提高，高达 34%，这是 PCL 链更好取向的结果。最终看到了对结晶的记忆效应，其中发现即使在将基质溶解在乙酸中并再次静电纺丝后，聚结的 PCL 基质的特征仍然保留。