Abstract

Milbemycin R, a novel spiro-heterocycle milbemycin, was obtained from the metabolites produced by the mutant strain S. bingchenggensis BCJ60B11. Its structure was determined by spectroscopic and spectrometric analyses including 1 D, 2 D NMR, IR, HR-ESI-MS data. The acaricidal and nematicidal activities of milbemycin R against Tetranychus cinnabarinus and Bursaphelenchus xylophilus were tested. Milbemycin R possessed better acaricidal activity than milbemycins A3/A4.

中文翻译：

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来自丙城根链霉菌基因工程菌株的新型螺杂环米尔倍霉素代谢物

摘要

Milbemycin R 是一种新型螺环杂环米尔倍霉素，是从突变菌株S. bingchenggensis BCJ60B11 产生的代谢物中获得的。其结构通过光谱和光谱分析确定，包括 1 D、2 D NMR、IR、HR-ESI-MS 数据。测试了米尔贝霉素 R 对朱砂叶螨和松材线虫的杀螨和杀线虫活性。米尔倍霉素R 比米尔倍霉素A3/A4 具有更好的杀螨活性。