Nonhuman primates (NHPs) are a critical component of translational/preclinical biomedical research due to the strong similarities between NHP and human physiology and disease pathology. In some cases, NHPs represent the most appropriate, or even the only, animal model for complex metabolic, neurological, and infectious diseases. The increased demand for and limited availability of these valuable research subjects requires that rigor and reproducibility be a prime consideration to ensure the maximal utility of this scarce resource. Here, we discuss a number of approaches that collectively can contribute to enhanced rigor and reproducibility in NHP research.

中文翻译：

---

提高非人类灵长类动物研究的严谨性和可重复性

由于 NHP 与人类生理学和疾病病理学之间的强烈相似性，非人类灵长类动物 (NHP) 是转化/临床前生物医学研究的重要组成部分。在某些情况下，NHP 代表了复杂代谢、神经和传染病的最合适甚至唯一的动物模型。对这些有价值的研究主题的需求增加和有限的可用性要求严格性和可重复性是确保这种稀缺资源的最大效用的首要考虑因素。在这里，我们讨论了一些共同有助于提高 NHP 研究的严谨性和可重复性的方法。