Herein we report the successful synthesis of stable silver nanoparticles (AgNPs) using 1,1′-(quinoxaline-2,3-diylbis(azanediyl))diethanol (QX) as the only stabilizer. The QX-AgNPs system was then employed as chromogenic probe for the selective detection of L-cysteine (Cys), Mg²⁺, and Sn²⁺ in the presence of interfering species. We discuss the role of pH for differentiation between Mg²⁺ and Sn²⁺ in terms of analyte-induced aggregation mechanisms. Limits of detection reached 2.7 nmol L⁻¹, 15 nmol L⁻¹ and 18 nmol L⁻¹ for Cys, and Mg²⁺ and Sn²⁺, respectively, which are levels comparable to other reported probes. Concerning Mg²⁺, the LOD found in this study was the lowest ever reported. The QX-AgNPs were also successfully employed in the quantification of Cys in urine and Mg²⁺ in tap water.

在此，我们报告了使用 1,1'-(quinoxaline-2,3-diylbis(azanediyl))二乙醇 (QX) 作为唯一稳定剂成功合成稳定的银纳米粒子 (AgNPs)。然后将 QX-AgNPs 系统用作显色探针，用于在存在干扰物质的情况下选择性检测L-半胱氨酸 (Cys)、Mg ²⁺和 Sn ²⁺。我们根据分析物诱导的聚集机制讨论了 pH 在区分 Mg ²⁺和 Sn ²⁺中的作用。Cys、Mg ²⁺和Sn ²⁺的检测限达到2.7 nmol L ^-1、15 nmol L ^-1和18 nmol L ^-1，分别是与其他报道的探针相当的水平。关于 Mg ²⁺，本研究中发现的 LOD 是有史以来最低的。QX-AgNPs 还成功地用于定量尿液中的 Cys 和自来水中的Mg ²⁺。