Objective

To compare the clinical pregnancy rate (CPR) and live birth rate (LBR) of embryo transfer episodes (ETEs) performed by Reproductive Endocrinology and Infertility fellows vs. those of ETEs performed by faculty physicians.

Design

Retrospective cohort analysis.

Setting

Academic reproductive endocrinology and infertility practice.

Patient(s)

In total, 3,073 ETEs for 1,488 unique patients were performed by fellows or faculty physicians between January 2009 and January 2020.

Intervention(s)

None.

Main Outcome Measure(s)

Clinical pregnancy rate and LBR.

Result(s)

Fifteen fellows performed 1,225 (39.9%) of 3,073 ETEs after completing 30 mock transfers. On comparing outcomes among fellowship years (FY1, FY2, and FY3), CPR (44.1% vs. 43.2% vs. 45.7%, respectively, P = .83) and LBR (39.1% vs. 38.1% vs. 38.4%, respectively, P = .97) were not significantly different. Fellowship year 1 fellows’ initial 30 ETEs vs. all the remaining FY1 ETEs had a significantly higher CPR (48.1% vs. 40.5%, respectively, P = .030) and LBR (45.4% vs. 34.3%, respectively, P = .001). There were no significant differences between faculty versus fellow ETEs in terms of CPR (43.0% vs. 45.0%, respectively, P = .30) or LBR (37.3% vs. 39.8%, respectively, P = .16), even after adjusting for patient age, body mass index, primary infertility diagnosis, autologous vs. donor oocyte, fresh vs. frozen embryo, number of embryos transferred, type of transfer catheter, and year of transfer (P = .32 for CPR, P = .22 for LBR).

Conclusion(s)

Appropriately trained FY1 fellows had success rates maintained throughout all FYs. There were no significant differences in clinical outcomes between fellow- and faculty-performed transfers. These data demonstrated that allowing fellows to perform live embryo transfers is not detrimental to clinical outcomes.

中文翻译：

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生殖内分泌学和不孕症研究员与教师进行的胚胎移植结果：11 年回顾性回顾

客观的

比较生殖内分泌和不孕症研究员与教职医师进行的胚胎移植事件 (ETE) 的临床妊娠率 (CPR) 和活产率 (LBR)。

设计

回顾性队列分析。

环境

学术生殖内分泌学和不孕症实践。

耐心）

2009 年 1 月至 2020 年 1 月期间，研究员或教职医师总共为 1,488 名独特患者进行了 3,073 次 ETE。

干预措施

没有。

主要观察指标）

临床妊娠率和LBR。

结果）

在完成 30 次模拟转移后，15 名研究员完成了 3,073 次 ETE 中的 1,225 次（39.9%）。在比较研究金年份（FY1、FY2 和 FY3）、CPR（分别为 44.1% vs. 43.2% vs. 45.7%，P = .83）和 LBR（分别为 39.1% vs. 38.1% vs. 38.4%）之间的结果时, P = .97) 没有显着差异。奖学金第一年的研究员最初的 30 个 ETE 与所有剩余的 FY1 ETE 的 CPR（分别为 48.1% 和 40.5%，P = .030）和 LBR（分别为 45.4% 和 34.3%，P = . 001)。在 CPR（分别为 43.0% 和 45.0%，P = .30）或 LBR（分别为 37.3% 和 39.8%，P= .16)，即使在调整了患者年龄、体重指数、原发性不孕症诊断、自体卵母细胞与供体卵母细胞、新鲜胚胎与冷冻胚胎、移植胚胎数量、移植导管类型和移植年份后 ( P = . CPR 为 32，LBR 为P = .22）。

结论

受过适当培训的 FY1 研究员在所有 FY 中都保持了成功率。研究员和教师进行的转移之间的临床结果没有显着差异。这些数据表明，允许研究员进行活胚胎移植不会损害临床结果。