Reported here is an efficient enantioselective transfer hydrogenation of cyclic oxocarbenium ions generated in situ through collapse of the corresponding acetal substrates. The asymmetric approach provides straightforward access to a variety of chiral α-aryl substituted 1,3-dihydroisobenzofurans in high yields with excellent enantioselectivities. α-Alkynyl substituted 1,3-dihydroisobenzofurans were also proved to be suitable substrates. In addition, when the reaction was performed at gram scale, the desired product was obtained in good yields with excellent enantioselectivity.

中文翻译：

---

Oxocarbenium 离子的对映选择性转移氢化能够不对称地获得 α-取代的 1,3-二氢异苯并呋喃

这里报道的是通过相应缩醛底物的塌陷原位生成的环状氧代碳鎓离子的有效对映选择性转移氢化。不对称方法提供了直接获得各种手性 α-芳基取代的 1,3-二氢异苯并呋喃的高产率和优异的对映选择性。α-炔基取代的 1,3-二氢异苯并呋喃也被证明是合适的底物。此外，当反应以克规模进行时，以良好的收率和优异的对映选择性获得了所需的产物。