In this study, polylactic acid (PLA) based polymer composite filaments containing titanium dioxide (titania, TiO₂), synthetic hydroxyapatite (HA), and natural hydroxyapatite (NHA) have been developed for biomedical applications. By using these composite filaments fabricated, 3D prints were easily printed on the fused deposition modeling (FDM) printer. The chemical and physical properties of PLA/HA/NHA/TiO₂ composite prints were investigated. According to the DSC/TGA analysis of the 3D printing samples, the maximum operating temperature of the composites formed in PLA/HA/NHA/TiO₂ blends was approximately 300 °C. With the addition of 1% HA/4% TiO₂ to PLA, the glass transition temperature was 71 °C and the melting temperature was 167 °C. According to FTIR analysis, HA/NHA/TiO₂ additives did not cause a change in the chemical structure of PLA. According to SEM analysis, TiO₂ caused raster gaps to decrease and HA caused raster lines to be smoother. In EDX and Mapping analysis, it was seen that HA/NHA/TiO₂ was homogeneously distributed in PLA. Stirring the PLA/HA/NHA/TiO₂ mixtures at 100 rpm for 12 h was sufficient for homogeneous distribution.

在这项研究中，基于聚乳酸 (PLA) 的聚合物复合长丝包含二氧化钛（二氧化钛，TiO ₂）、合成羟基磷灰石（HA）和天然羟基磷灰石（NHA）已被开发用于生物医学应用。通过使用这些制造的复合长丝，可以轻松地在熔融沉积成型 (FDM) 打印机上打印 3D 打印件。研究了 PLA/HA/NHA/TiO ₂复合印刷品的化学和物理性能。根据 3D 打印样品的 DSC/TGA 分析，在 PLA/HA/NHA/TiO ₂共混物中形成的复合材料的最高工作温度约为 300 °C。添加 1% HA/4% TiO ₂PLA，玻璃化转变温度为 71 °C，熔融温度为 167 °C。根据 FTIR 分析，HA/NHA/TiO ₂添加剂不会导致 PLA 的化学结构发生变化。根据SEM分析，TiO ₂导致光栅间隙减小，HA导致光栅线更平滑。在 EDX 和 Mapping 分析中，可以看出 HA/NHA/TiO ₂均匀分布在 PLA 中。以 100 rpm 的速度搅拌 PLA/HA/NHA/TiO ₂混合物 12 小时足以均匀分布。