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Biological and pharmacological activities of noscapine: Focusing on its receptors and mechanisms
Biofactors ( IF 5.0 ) Pub Date : 2021-09-17 , DOI: 10.1002/biof.1781
Fahimeh Nourbakhsh 1 , Vahid Reza Askari 2, 3
Affiliation  

Noscapine has been mentioned as one of the effective drugs with potential therapeutic applications. With few side effects and amazing capabilities, noscapine can be considered different from other opioids-like structure compounds. Since 1930, extensive studies have been conducted in the field of pharmacological treatments from against malaria to control cough and cancer treatment. Furthermore, recent studies have shown that noscapine and some analogues, like 9-bromonoscapine, amino noscapine, and 9-nitronoscapine, can be used to treat polycystic ovaries syndrome, stroke, and other diseases. Given the numerous results presented in this field and the role of different receptors in the therapeutic effects of noscapine, we aimed to review the properties, therapeutic effects, and the role of receptors in the treatment of noscapine.

中文翻译:

那可品的生物和药理活性:关注其受体和机制

Noscapine 被认为是具有潜在治疗应用的有效药物之一。诺斯卡品副作用小,功效惊人,可以说是有别于其他类阿片类结构化合物。自 1930 年以来,在药物治疗领域进行了广泛的研究,从抗疟疾到控制咳嗽和癌症治疗。此外,最近的研究表明,诺斯卡品和一些类似物,如 9-溴香豆素、氨基诺斯卡品和 9-硝基香豆素,可用于治疗多囊卵巢综合征、中风和其他疾病。鉴于该领域的众多结果以及不同受体在诺斯卡品治疗效果中的作用,我们旨在回顾受体在诺斯卡品治疗中的特性、治疗效果和作用。
更新日期:2021-09-17
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