Periprosthetic shoulder infection (PSI) remains a devastating complication after total shoulder arthroplasty (TSA). Furthermore, there is a paucity in the literature regarding its diagnostic and therapeutic management, especially the absence of therapy concepts devised exclusively for PSI. The aim of the presenting study is to examine the characteristics and outcome of patients with PSI who were treated according to well-established algorithms developed originally for periprosthetic joint infection (PJI) of the hip and knee and determine if these algorithms can be applied to PSI. This single-center case series included all patients with a PSI presenting between 2010 and 2020. Recorded parameters included age, sex, affected side, BMI, ASA score, Charlson comorbidity index, preoperative anticoagulation, indication for TSA (fracture, osteoarthritis or cuff-arthropathy), and type of infection (acute or chronic PSI). The outcome was divided into treatment failure or infect resolution. Staphylococcus epidermidis and aureus were the commonest infecting pathogens. Acute PSI was mainly treated with debridement, irrigation, and retention of the prosthesis (DAIR) and chronic cases with two/multiple-stage exchange. The treatment failure rate was 10.5%. C-reactive protein was preoperatively elevated in 68.4% of cases. The mean number of operative revisions was 3.6 ± 2.6, and the mean total duration of antibiotic treatment was 72.4 ± 41.4 days. The most administered antibiotic was a combination of clindamycin and fluoroquinolone. In summary, the data of the current study suggest that therapeutical algorithms and recommendations developed for the treatment of PJI of the hip and knee are also applicable to PSI.

中文翻译：

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肩关节假体周围感染：19 例单中心系列病例的特征和 5 年结果

肩关节假体周围感染 (PSI) 仍然是全肩关节置换术 (TSA) 后的一种破坏性并发症。此外，关于其诊断和治疗管理的文献很少，尤其是缺乏专为 PSI 设计的治疗概念。本研究的目的是检查根据最初为髋关节和膝关节假体周围感染 (PJI) 开发的完善算法治疗的 PSI 患者的特征和结果，并确定这些算法是否可以应用于 PSI . 该单中心病例系列包括 2010 年至 2020 年间出现 PSI 的所有患者。记录的参数包括年龄、性别、患侧、BMI、ASA 评分、Charlson 合并症指数、术前抗凝、TSA 适应症（骨折、骨关节炎或袖带关节病）和感染类型（急性或慢性 PSI）。结果分为治疗失败或感染消退。表皮葡萄球菌和金黄色葡萄球菌是最常见的感染病原体。急性PSI主要采用清创、冲洗、保留假体（DAIR）和两期/多期置换治疗慢性病例。治疗失败率为10.5%。68.4% 的病例术前 C 反应蛋白升高。手术翻修的平均次数为 3.6 ± 2.6，抗生素治疗的平均总持续时间为 72.4 ± 41.4 天。施用最多的抗生素是克林霉素和氟喹诺酮的组合。总之，