Heart failure with reduced ejection fraction (HFrEF) and chronic obstructive pulmonary disease (COPD) individually cause significant morbidity and mortality. Their coexistence is associated with even worse outcomes, partly due to suboptimal heart failure therapy, especially underutilisation of beta-blockers. Our aim was to investigate outcomes in HFrEF patients with and without COPD, and the effects of mineralocorticoid receptor antagonists (MRAs) on outcomes.

中文翻译：

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盐皮质激素受体拮抗剂对射血分数降低的心力衰竭慢性阻塞性肺疾病患者 EMPHASIS-HF 和 RALES 的影响

射血分数降低的心力衰竭（HFrEF）和慢性阻塞性肺疾病（COPD）分别导致显着的发病率和死亡率。它们的共存会带来更糟糕的结果，部分原因是心力衰竭治疗不理想，尤其是β受体阻滞剂的利用不足。我们的目的是调查患有和不患有 COPD 的 HFrEF 患者的结局，以及盐皮质激素受体拮抗剂 (MRA) 对结局的影响。