Social media forums provide a window into how gay, bisexual, and other men who have sex with men talk about pre-exposure prophylaxis for HIV prevention (PrEP) outside of research contexts. To examine information exchange about this important pillar of HIV prevention, discussions around PrEP were collected from the r/askgaybros subreddit of the social media site Reddit (2014–2019). Post titles and asks were qualitatively coded to identify themes describing the primary purpose of the post. In all, 1163 PrEP posts were identified, and a 23.3-fold increase in post volume was seen from 2014 (n = 20) to 2019 (n = 466). The most common post type was a mention of PrEP in a post primarily discussing: an assessment of risk after a sexual encounter (19.2%); a sexual or romantic relationship (6.0%); or other (29.3%). Access challenges (19.1%), information seeking (17.5%), and the cultural effects of PrEP on the gay community (16.3%) were other common themes. Posts regarding the initiation of PrEP (11.8%) and PrEP side-effects (9.4%) were moderately represented. Posts addressing promotion, shade, stigma, and usage were infrequent (≤ 5.5% of posts, respectively). Over time, discussion of PrEP has increased exponentially on r/askgaybros, which may reflect the normalization of PrEP. Qualitative analysis of these posts can be a rich source of data for scientists, practitioners, and healthcare providers interested in increasing uptake of PrEP and decreasing barriers to its use.

社交媒体论坛提供了一个窗口，让我们了解同性恋、双性恋和其他男男性行为者如何在研究环境之外谈论暴露前预防艾滋病毒预防 (PrEP)。为了检查有关艾滋病毒预防这一重要支柱的信息交流，从社交媒体网站 Reddit（2014-2019 年）的 r/askgaybros 子版块收集了围绕 PrEP 的讨论。帖子标题和问题被定性编码，以识别描述帖子主要目的的主题。总共确定了 1163 个 PrEP 帖子，从 2014 年（n = 20）到 2019 年（n = 466），帖子数量增加了 23.3 倍。最常见的帖子类型是在主要讨论以下内容的帖子中提及 PrEP：性接触后风险评估（19.2%）；性或浪漫关系（6.0%）；或其他（29.3%）。访问挑战（19.1%），寻求信息 (17.5%) 和 PrEP 对同性恋社区的文化影响 (16.3%) 是其他常见主题。关于 PrEP 启动 (11.8%) 和 PrEP 副作用 (9.4%) 的帖子有中度代表。涉及促销、阴影、污名和使用的帖子很少（分别≤ 5.5% 的帖子）。随着时间的推移，关于 PrEP 的讨论在 r/askgaybros 上呈指数增长，这可能反映了 PrEP 的标准化。对这些帖子的定性分析可以成为科学家、从业人员和医疗保健提供者的丰富数据来源，他们有兴趣增加对 PrEP 的吸收并减少其使用障碍。涉及促销、阴影、污名和使用的帖子很少（分别≤ 5.5% 的帖子）。随着时间的推移，关于 PrEP 的讨论在 r/askgaybros 上呈指数增长，这可能反映了 PrEP 的标准化。对这些帖子的定性分析可以成为科学家、从业人员和医疗保健提供者的丰富数据来源，他们有兴趣增加对 PrEP 的吸收并减少其使用障碍。涉及促销、阴影、污名和使用的帖子很少（分别≤ 5.5% 的帖子）。随着时间的推移，关于 PrEP 的讨论在 r/askgaybros 上呈指数增长，这可能反映了 PrEP 的标准化。对这些帖子的定性分析可以成为科学家、从业人员和医疗保健提供者的丰富数据来源，他们有兴趣增加对 PrEP 的吸收并减少其使用障碍。