Nanoscale structures demonstrate considerable potential utility in the construction of nanorobots, nanomachines, and many other devices. In this study, a hexagonal DNA origami ring was assembled and visualized via atomic force microscopy. The DNA origami shape could be programmed into either a hexagonal or linear shape with an open or folded pattern. The flexible origami was robust and switchable for dynamic pattern recognition. Its edges were folded by six bundles of DNA helices, which could be opened or folded in a honeycomb shape. Additionally, the edges were programmed into a concave-convex pattern, which enabled linkage between the origami and dipolymers. Furthermore, biotin-streptavidin labels were embedded at each edge for nanoscale calibration. The atomic force microscopy results demonstrated the stability and high-yield of the flexible DNA origami ring. The polymorphous nanostructure is useful for dynamic nano-construction and calibration of structural probes or sensors.

中文翻译：

---

灵活的六边形 DNA 折纸的可编程和可扩展组装

纳米级结构在构建纳米机器人、纳米机器和许多其他设备中显示出相当大的潜在效用。在这项研究中，通过原子力显微镜组装和可视化了一个六角形 DNA 折纸环。DNA折纸形状可以编程为具有开放或折叠图案的六边形或线性形状。灵活的折纸对于动态模式识别非常强大且可切换。它的边缘被六束DNA螺旋折叠起来，可以打开或折叠成蜂窝状。此外，边缘被编程为凹凸图案，从而实现了折纸和二聚物之间的连接。此外，生物素-链霉亲和素标签嵌入在每个边缘进行纳米级校准。原子力显微镜结果证明了柔性 DNA 折纸环的稳定性和高产率。多形纳米结构可用于结构探针或传感器的动态纳米构造和校准。