Despite many discoveries over the past 20 years regarding the etiopathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies continues to rise. For this reason, it was clear that other strategies were needed to eliminate biofilms. In this review, the literature database was searched for studies on locally delivered synthetic agents that exhibit anti-biofilm properties and their potential use in the treatment of two important oral diseases: periodontitis and peri-implantitis.

中文翻译：

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用于治疗牙周炎和种植体周围炎的具有抗生物膜特性的局部口服给药剂。叙事评论

尽管在过去的 20 年里有许多关于牙周病和种植体周围疾病的发病机制的发现，以及我们对微生物生物膜的理解取得了重大进展，但这些病理的发生率仍在继续上升。出于这个原因，很明显需要其他策略来消除生物膜。在这篇综述中，检索了文献数据库中关于具有抗生物膜特性的局部递送合成药物及其在治疗两种重要口腔疾病（牙周炎和种植体周围炎）中的潜在用途的研究。