Despite many discoveries over the past 20 years regarding the etiopathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies continues to rise. For this reason, it was clear that other strategies were needed to eliminate biofilms. In this review, the literature database was searched for studies on locally delivered synthetic agents that exhibit anti-biofilm properties and their potential use in the treatment of two important oral diseases: periodontitis and peri-implantitis.

中文翻译：

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具有抗生物膜特性的局部口服给药剂可用于治疗牙周炎和种植体周围炎。叙事回顾


尽管过去 20 年在牙周和种植体周围疾病的发病机制方面取得了许多发现，并且我们对微生物生物膜的理解也取得了重大进展，但这些疾病的发病率仍在持续上升。因此，很明显需要其他策略来消除生物膜。在这篇综述中，检索了文献数据库，以查找有关具有抗生物膜特性的局部递送合成药物及其在治疗两种重要口腔疾病：牙周炎和种植体周围炎中的潜在用途的研究。