Bisphenol A (BPA), also known as 2,2,-bis(4-hydroxyphenyl) propane, is a common component of plastics worldwide. However, it has been shown to act as an endocrine disruptor with some hormonal functions. Furthermore, high levels of BPA have been related to the development of cardiovascular events and the activation of carcinogenesis pathways. Patients with chronic kidney disease (CKD) have higher serum concentrations of BPA due to their impaired renal function. This situation is aggravated in CKD patients requiring dialysis, because the BPA content of dialysis devices (such as, for example, the filters) is added to the lack of excretion. In addition to the development of BPA-free dialysis filters, some techniques can contribute to the reduction of BPA levels in these patients. The aim of this review is to illustrate the impact of BPA on dialysis patients and suggest some strategies to reduce its inherent risks.

中文翻译：

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保护透析患者免受双酚 A 侵害的策略

双酚 A (BPA)，也称为 2,2,-双(4-羟基苯基)丙烷，是全球塑料的常见成分。然而，它已被证明可作为具有某些激素功能的内分泌干扰物。此外，高水平的 BPA 与心血管事件的发展和致癌途径的激活有关。慢性肾病 (CKD) 患者由于肾功能受损，血清 BPA 浓度较高。这种情况在需要透析的 CKD 患者中更加严重，因为透析装置（例如过滤器）的 BPA 含量增加了排泄的不足。除了开发不含 BPA 的透析过滤器外，一些技术还有助于降低这些患者的 BPA 水平。