Mini-Reviews in Organic Chemistry ( IF 1.9 ) Pub Date : 2021-08-31 , DOI: 10.2174/1570193x17999200820163234 Mohamed Ibrahim Elzagheid 1
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Nucleosides and their analogues have been in use for many years and have become essential for treating patients with viral infections. Many additional nucleoside drugs have been approved over the past decades. This strongly demonstrates how important these compounds are and the crucial role they play. Given that a significant amount of research and literature has been documented regarding nucleoside analogues, this review article mainly focuses on nucleosides and nucleoside analogues that have proven to play a significant role in the treatment of known viral infections. This article covers the names, structures, applications, toxicity, and mode of action of relevant nucleoside analogues.
中文翻译：
作为新兴抗病毒药物的核苷和核苷类似物
核苷及其类似物已使用多年，已成为治疗病毒感染患者的必要条件。在过去的几十年里，已经批准了许多其他核苷药物。这有力地证明了这些化合物的重要性及其发挥的关键作用。鉴于已记录了大量关于核苷类似物的研究和文献，本文主要关注核苷和核苷类似物，它们已被证明在治疗已知病毒感染中发挥重要作用。本文涵盖相关核苷类似物的名称、结构、应用、毒性和作用方式。
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